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ArXiv submission?

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I'd like to put our arseniclife submission to Science onto the arXiv server so that anyone who's interested can read it.  Not many biologists use arXiv (it's mainly a physics thing) but it's a very convenient place to post manuscripts and other documents.  And its use by physicists provides a great precedent for open science, because manuscripts are posted there and submitted for formal publication in peer-reviewed journals.

However, I'd like to first find out whether Science has any policy about arXiv pre-publication.  Their Instructions to Authors say:
 Distribution on the Internet may be considered prior publication and may compromise the originality of the paper as a submission to Science. Please contact the editors with questions regarding allowable postings.
Has anyone had direct experience with this?  I think I'd better send out a tweet...

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